Risk of atrial fibrillation in individuals with dysglycemia and diabetes

Diabetes is a risk factor for atrial fibrillation (AF), and increases the of thromboembolic events in persons with AF. However, link between two conditions not fully elucidated. Few studies have investigated association dysglycemia incident We AF prognosis according to diabetes status. The Copenhagen Primary Care Laboratory Database was merged data on medical prescriptions, in- outpatient contacts vital status by use Cox regression models. Of 354.807 individuals hemoglobin A1c (HbA1c) measurement, 28.541 (8 %) had known diabetes, 13.038 (4 new onset 27.754 prediabetes (HbA1c 42-47 mmol/mol). Persons > 42 mmol/mol) were older, more men, they lower level education likely be living alone. observed gradual increase developing from HbA1c levels 40 60 mmol/mol. In adjusted analyses we found stepwise hazard normoglycemia over (no diabetes: 1.00 [ref.]; prediabetes: 1.12 [1.08–1.16]; new-onset 1.16 [1.10–1.22]; 1.15 [1.11–1.20]). significant higher stroke, cardiovascular all-cause mortality. Increasing associated an increased those similar AF, however cardiovascular-